After I installed VS2008SP1 I got this an error in Vista/IIS7.

 I get this when running in Integrated Pipeline:

[PlatformNotSupportedException: The DefaultHttpHandler.BeginProcessRequest method is not supported by IIS integrated pipeline mode.]
System.Web.DefaultHttpHandler.BeginProcessRequest(HttpContext context, AsyncCallback callback, Object state) +2871035
EPiServer.Web.StaticFileHandler.BeginProcessRequest(HttpContext context, AsyncCallback callback, Object state) +120
System.Web.CallHandlerExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute() +8674594
System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously) +155

Integrated have alway worked before... I dont know what else has changed (than installing VS2008SP1/.Net 3.5SP1)

 When changing to Classic mode, I get this:

[HttpException (0x80004005): Failed to Execute URL.]
System.Web.Hosting.ISAPIWorkerRequestInProcForIIS6.BeginExecuteUrl(String url, String method, String childHeaders, Boolean sendHeaders, Boolean addUserIndo, IntPtr token, String name, String authType, Byte[] entity, AsyncCallback cb, Object state) +2004965
System.Web.HttpResponse.BeginExecuteUrlForEntireResponse(String pathOverride, NameValueCollection requestHeaders, AsyncCallback cb, Object state) +390
System.Web.DefaultHttpHandler.BeginProcessRequest(HttpContext context, AsyncCallback callback, Object state) +223
EPiServer.Web.StaticFileHandler.BeginProcessRequest(HttpContext context, AsyncCallback callback, Object state) +120
System.Web.CallHandlerExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute() +8674594
System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously) +155

 Any ideas?